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A RARE CASE OF RENAL CLEAR CELL CARCINOMA ACROMETASTASIS AND ITS MANAGEMENT

Yıl 2023, Cilt: 86 Sayı: 3, 272 - 274, 26.10.2023

Erol Kozanoğlu Bora Akalın Dicle Aksöyler Ömer Berköz

https://doi.org/10.26650/IUITFD.1290975

Öz

Metastases that affect the distal regions of the upper and the lower extremities are called acrometastases and they affect the bones and the overlying tissues. Various cancer types may have single or multiple acrometastases. A sixty-four-year-old female patient had a painful and enlarging mass at the tip of the fifth digit of her right hand. The lesion appeared as a red macule at the junction between the nail plate and the hyponychium. The patient was in her seventh postoperative year after a left-sided total nephrectomy with a histopathological diagnosis of renal clear cell carcinoma. Due to multiple metastases to the spleen and left femoral head, she had been treated with twenty sessions of radiotherapy and she was under nivolumab therapy twice a month for two years. A punch biopsy revealed a gland forming, CD 10, PAX 8 and vimentin-positive renal clear cell carcinoma metastasis. The patient was treated with amputation of the distal phalanx. Although rare, acrometastasis should be included in the differential diagnosis of patients with a history of renal clear cell carcinoma.

Anahtar Kelimeler

Acrometastasis amputation hand phalanx renal clear cell carcinoma

Proje Numarası

YOKTUR.

Kaynakça

  • Flynn C, Danjoux C, Wong J, Christakis M, Rubenstein J, Yee A, et al. Two cases of acrometastasis to the hands and review of the literature. Curr Oncol 2008;15(5):51-8. [CrossRef] google scholar
  • Milionis V, Vlachodimitropoulos D, Goutas D, Goutas N. Acrometastases in Renal Cell Carcinoma: A Case Report and Review of Literature. Clin Oncol Case Rep 2020;2:2. google scholar
  • Rommer E, Leilabadi SN, Lam G, Soltani A, Ellis CV, Rizvi M, et al. Metastasis of hepatocellular and renal cell carcinoma to the hand. Plast Reconstr Surg Glob Open 2014;1(9):e83. [CrossRef] google scholar
  • Hernández-Cortés P, Caba-Molina M, Gómez-Sánchez R, Ríos-Peregrina R. Renal clear cell carcinoma acrometastasis. an unusual terminal condition. J Hand Microsurg 2015;7(01):149-51. [CrossRef] google scholar
  • Kamala LH, Ranjith S, Benson R. Cutaneous acral metastasis from renal cell carcinoma—a case report. Indian J Surg Oncol 2019:1-3. https://doi.org/10.1007/s13193-019-00961- 2. [CrossRef] google scholar
  • Capitanio U, Bensalah K, Bex A, Boorjian SA, Bray F, Coleman J, et al. Epidemiology of renal cell carcinoma. Eur Urol 2019;75(1):74-84. [CrossRef] google scholar
  • Padala SA, Barsouk A, Thandra KC, Saginala K, Mohammed A, Vakiti A, et al. Epidemiology of renal cell carcinoma. World J Oncol 2020;11(3):79-87. [CrossRef] google scholar
  • Ljungberg B, Albiges L, Abu-Ghanem Y, Bedke J, Capitanio U, Dabestani S, et al. European Association of Urology guidelines on renal cell carcinoma: the 2022 update. Eur Urol. 2022. [CrossRef] google scholar
  • Wolfe SW, Pederson WC, Kozin SH, Cohen MS. Green’s Operative Hand Surgery. Two Volumes. 5th Edition. Elsevier, Churchill Livingstone. 2005. google scholar

NADİR BİR RENAL BERRAK HÜCRELİ KARSİNOM AKROMETASTAZI OLGUSU VE OLGUYA YAKLAŞIM

Yıl 2023, Cilt: 86 Sayı: 3, 272 - 274, 26.10.2023

Erol Kozanoğlu Bora Akalın Dicle Aksöyler Ömer Berköz

https://doi.org/10.26650/IUITFD.1290975

Öz

Üst ve alt ekstremitenin distal kısımlarını etkileyen metastazlara akrometastaz denir ve bu tabloda, kemikler ve üzerlerindeki dokular etkilenir. Farklı kanser türleri tekli veya çoklu akrometastazlar yapabilir. Altmış dört yaşındaki bir kadın hasta, sağ elinin beşinci parmağının ucunda ortaya çıkan ağrılı ve sürekli büyüyen bir kitle ile polikliniğe başvurmuştur. Lezyon, tırnak plağı ve hiponişyum kesişimindeki kırmızı bir maküldür. Hasta, yedi yıl önce histopatolojik tanısı renal berrak hücreli karsinom olan bir kitle nedeniyle sol taraflı total nefrektomi geçirmiştir. Hastanın dalağında ve sol femur başında çoklu metastazları olduğundan hastaya yirmi seans radyoterapi uygulanmıştır. Hastaya son iki yıldır, ayda iki kez nivolumab tedavisi verilmiştir. Yapılan punch biyopside CD 10, PAX 8 ve vimentin pozitif olan ve gland oluşturan renal berrak hücreli karsinom metastazı saptanmıştır. Hastaya distal falanks ampütasyonu ameliyatı yapılmıştır. Renal berrak hücreli karsinom öyküsü olan hastalarda görülen parmak lezyonlarının ayırıcı tanısında, nadir de olsa akrometastaz göz önünde bulundurulmalıdır.

Anahtar Kelimeler

Akrometastaz amputasyon el falanks renal berrak hücreli karsinom

Destekleyen Kurum

YOKTUR.

Proje Numarası

YOKTUR.

Kaynakça

  • Flynn C, Danjoux C, Wong J, Christakis M, Rubenstein J, Yee A, et al. Two cases of acrometastasis to the hands and review of the literature. Curr Oncol 2008;15(5):51-8. [CrossRef] google scholar
  • Milionis V, Vlachodimitropoulos D, Goutas D, Goutas N. Acrometastases in Renal Cell Carcinoma: A Case Report and Review of Literature. Clin Oncol Case Rep 2020;2:2. google scholar
  • Rommer E, Leilabadi SN, Lam G, Soltani A, Ellis CV, Rizvi M, et al. Metastasis of hepatocellular and renal cell carcinoma to the hand. Plast Reconstr Surg Glob Open 2014;1(9):e83. [CrossRef] google scholar
  • Hernández-Cortés P, Caba-Molina M, Gómez-Sánchez R, Ríos-Peregrina R. Renal clear cell carcinoma acrometastasis. an unusual terminal condition. J Hand Microsurg 2015;7(01):149-51. [CrossRef] google scholar
  • Kamala LH, Ranjith S, Benson R. Cutaneous acral metastasis from renal cell carcinoma—a case report. Indian J Surg Oncol 2019:1-3. https://doi.org/10.1007/s13193-019-00961- 2. [CrossRef] google scholar
  • Capitanio U, Bensalah K, Bex A, Boorjian SA, Bray F, Coleman J, et al. Epidemiology of renal cell carcinoma. Eur Urol 2019;75(1):74-84. [CrossRef] google scholar
  • Padala SA, Barsouk A, Thandra KC, Saginala K, Mohammed A, Vakiti A, et al. Epidemiology of renal cell carcinoma. World J Oncol 2020;11(3):79-87. [CrossRef] google scholar
  • Ljungberg B, Albiges L, Abu-Ghanem Y, Bedke J, Capitanio U, Dabestani S, et al. European Association of Urology guidelines on renal cell carcinoma: the 2022 update. Eur Urol. 2022. [CrossRef] google scholar
  • Wolfe SW, Pederson WC, Kozin SH, Cohen MS. Green’s Operative Hand Surgery. Two Volumes. 5th Edition. Elsevier, Churchill Livingstone. 2005. google scholar
Toplam 9 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Hizmetleri ve Sistemleri (Diğer)
Bölüm Olgu Sunumu
Yazarlar

Erol Kozanoğlu 0000-0003-1192-9520

Bora Akalın 0000-0002-5654-2082

Dicle Aksöyler 0000-0002-3692-8893

Ömer Berköz 0000-0001-8063-9995

Proje Numarası YOKTUR.
Yayımlanma Tarihi 26 Ekim 2023
Gönderilme Tarihi 2 Mayıs 2023
Yayımlandığı Sayı Yıl 2023 Cilt: 86 Sayı: 3

Kaynak Göster

APA Kozanoğlu, E., Akalın, B., Aksöyler, D., Berköz, Ö. (2023). A RARE CASE OF RENAL CLEAR CELL CARCINOMA ACROMETASTASIS AND ITS MANAGEMENT. Journal of Istanbul Faculty of Medicine, 86(3), 272-274. https://doi.org/10.26650/IUITFD.1290975
AMA Kozanoğlu E, Akalın B, Aksöyler D, Berköz Ö. A RARE CASE OF RENAL CLEAR CELL CARCINOMA ACROMETASTASIS AND ITS MANAGEMENT. İst Tıp Fak Derg. Ekim 2023;86(3):272-274. doi:10.26650/IUITFD.1290975
Chicago Kozanoğlu, Erol, Bora Akalın, Dicle Aksöyler, ve Ömer Berköz. “A RARE CASE OF RENAL CLEAR CELL CARCINOMA ACROMETASTASIS AND ITS MANAGEMENT”. Journal of Istanbul Faculty of Medicine 86, sy. 3 (Ekim 2023): 272-74. https://doi.org/10.26650/IUITFD.1290975.
EndNote Kozanoğlu E, Akalın B, Aksöyler D, Berköz Ö (01 Ekim 2023) A RARE CASE OF RENAL CLEAR CELL CARCINOMA ACROMETASTASIS AND ITS MANAGEMENT. Journal of Istanbul Faculty of Medicine 86 3 272–274.
IEEE E. Kozanoğlu, B. Akalın, D. Aksöyler, ve Ö. Berköz, “A RARE CASE OF RENAL CLEAR CELL CARCINOMA ACROMETASTASIS AND ITS MANAGEMENT”, İst Tıp Fak Derg, c. 86, sy. 3, ss. 272–274, 2023, doi: 10.26650/IUITFD.1290975.
ISNAD Kozanoğlu, Erol vd. “A RARE CASE OF RENAL CLEAR CELL CARCINOMA ACROMETASTASIS AND ITS MANAGEMENT”. Journal of Istanbul Faculty of Medicine 86/3 (Ekim 2023), 272-274. https://doi.org/10.26650/IUITFD.1290975.
JAMA Kozanoğlu E, Akalın B, Aksöyler D, Berköz Ö. A RARE CASE OF RENAL CLEAR CELL CARCINOMA ACROMETASTASIS AND ITS MANAGEMENT. İst Tıp Fak Derg. 2023;86:272–274.
MLA Kozanoğlu, Erol vd. “A RARE CASE OF RENAL CLEAR CELL CARCINOMA ACROMETASTASIS AND ITS MANAGEMENT”. Journal of Istanbul Faculty of Medicine, c. 86, sy. 3, 2023, ss. 272-4, doi:10.26650/IUITFD.1290975.
Vancouver Kozanoğlu E, Akalın B, Aksöyler D, Berköz Ö. A RARE CASE OF RENAL CLEAR CELL CARCINOMA ACROMETASTASIS AND ITS MANAGEMENT. İst Tıp Fak Derg. 2023;86(3):272-4.
 Kapak Resmi İndir

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