Derleme
Yıl 2016,
Cilt: 2 Sayı: 2, 165 - 169, 01.06.2016
Öz
Alkol birçok organ ve dokuda (özellikle beyin ve karaciğer) doza ve kullanım süresine bağlı olarak hasar oluşturabilen bir toksindir. Doğum öncesi(prenatal) dönemde anne tarafından kullanılan alkol, fetal alkol sendromuna neden olabilmektedir. Fetal alkol sendromu ilk olarak 1970’li yıllarınbaşında, alkol kullanma alışkanlığını gebelikte de sürdüren anneden doğan bebeklerde görülen büyüme bozukluğu, yüz bölgesi anormallikleri vemental gerilik olarak tanımlanmıştır. Gebeliğin ilk üç ayında kullanılan alkol fetus üzerinde düşüğe, organogenez döneminde organlarda hasara,gebeliğin ikinci üç aylık döneminde hücrelerdeki fetotoksik etkisiyle merkezi sinir sisteminde ağır hasara neden olabilmektedir. Bu derlemede doğumöncesi alkol kullanımı sonucu oluşan oksidatif stres ve antioksidan savunma mekanizması hakkında bilgiler sunulmuştur.
Anahtar Kelimeler
Antioksidanlar fetal alkol sendromu oksidatif stres gebelikte alkol kullanımı
Kaynakça
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Toplam 38 adet kaynakça vardır.
Ayrıntılar
| Bölüm | Derleme |
|---|---|
| Yazarlar | |
| Yayımlanma Tarihi | 1 Haziran 2016 |
| Yayımlandığı Sayı | Yıl 2016 Cilt: 2 Sayı: 2 |
